Link between MRI, clinical exams missing in some MS patients

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Recent research shows physical disability and brain lesion volume may not be directly linked in patients with multiple sclerosis (MS).

The study, published in the Journal of Neuroimaging, examined MS patients, who show symptoms in many forms, including limited disability many years after diagnosis to severe physical limitations early on. Researchers found a significant minority showed a dissociation between MRI findings and clinical examinations.

“Dissociation may occur between physical disability and cerebral lesion volume in either direction in patients with MS. Type of MS, brain atrophy and spinal cord lesions may help to bridge this dissociation,” said Bakshi, a senior neurologist at Brigham and Women’s Hospital and director of the Laboratory for Neuroimaging Research at Boston’s Partners Multiple Sclerosis Center.

Read more about the study's findings here: